Hemoglobin kinetics and the effect of organic phosphates.
نویسندگان
چکیده
A kinetic model based on allosteric mechanisms of cooperativity fits the experimentally observed phosphate dependence of hemoglobin reactions. Subunit inequivalence is found to be important in analyzing hemoglobin kinetics. The observed increase in the rate of deoxygenation in the presence of organic phosphates is primarily related to the increased rate of dissociation of the second oxygen molecule.
منابع مشابه
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ورودعنوان ژورنال:
- Science
دوره 186 4167 شماره
صفحات -
تاریخ انتشار 1974